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As RandD productivity is declined and development times were lengthened, as clinical trials are becoming more complex and costly there was sharp rise in RandD expenditure. Social factors includes the demographic and cultural aspects of the external macro environment these factors effects customers needs and the size of potential markets, some social factors include health consciousness, population growth rate, age distribution, emphasis on safety and carrier attitudes. ageing populations are creating pressure on healthcare funding systems as over 65 consumes four times more than that of below 65 which leads to more expensive technology solutions and increase in patient expectations had created an unsustainable situation to the industry. Some countries cannot enjoy universal coverage system and latest treatments because they are not funded by the insurance companies like USA which can afford latest technology but cannot share the benefits because of increasing populations in different parts of the world. In developed countries consumer are benefited by the insurance and can afford ethical drugs but the countries who cannot afford to ethical drugs are switching to generic to save coast which pressuring pharmacists to substitute generic drug as the first choice, patented drugs are only used if generic drug fails. The OTCover the counter comprise of 20% of market which may purchase without prescription specially OTC is more in developing countries and also for these the patented drug companies has introduce disease management initiatives to attack the challenges from generic. Some consumer does not want to use biopharmaceuticals because they genetically done. Technological factors can lower barriers to entry, reduce minimum efficient production levels and influence outsourcing decisions. Some of the technological factors includes RandD activity, technology incentivise and rate of technology change. the technology is an competitive advantage to the companies and success of RandD lays in team working, knowledge management and close relation with external flexible and some indicates lean and flexible operations and out sourcing is a gate way of success not only these there are many questions raised that the investment on RandD is could not sustain for example in 2005 there are nearly 650 cancers drugs in development. The utilization of technology is very expensive because it includes latest instruments which is possible only for developed countries to use technology because they are funded by insurance companies and product developed by this technology cannot afford in developing countries because of its huge investment.
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In the late 1970s he moved to New York and enrolled in a master's program at Columbia to study international diplomacy. He knew that Israel had nuclear arms, and that India had tested its own device the "Smiling Buddha" of 1974, but he was not aware of Pakistan's ongoing program to respond in kind. If he thought about nuclear weapons at all, it was in the conventional terms of the Cold War turning hot. In July of 1981 the realities of proliferation were briefly thrust upon him when the Israeli Air Force bombed the French built Osirak reactor in Iraq, ending a secret attempt by Saddam Hussein to extract plutonium from spent fuel and acquire a nuclear arsenal of his own. But Hibbs did not imagine that he himself would ever be involved in such matters. He had a talent for language that allowed him eventually to learn German, Dutch, and French, as well as some Russian and a little Chinese. After leaving Columbia he stayed on in New York, working as a freelance consultant and editor, primarily for a German government office, but he found it difficult to earn a living, and so left for Europe, from which he has never permanently returned. For a while he lived in London, doing research for the Financial Times in the energy businessan area previously unknown to him, but of sufficient depth to engage his mind. He moved to Bonn, where he continued the same work and contributed occasionally to Business Week. His writing was concise. He was in no sense yet anything like a spy.
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There is no obvious method to identify the direction of influence, without detailed knowledge of the relationship between an NGO and a government. Environmental NGOs may have either type of funding relationship. Conservation and research groups may happily obtain government funds to support their programs: some are innovative and some are not. Beyond these situations, radical campaigning groups may be unwilling and unable to attract government funds. While a political party is not regarded as an NGO and cannot gain recognition at the UN, a small number of transnational groupings of political parties do gain consultative status with ECOSOC. There are also several groups of parliamentarians with consultative status. No problems have arisen with either group, because they have carefully avoided trying to involve the UN in the "internal affairs of states". Human rights NGOs feel aggrieved that the same principle is applied to them, even though one of the purposes of ECOSOC is "promoting respect for, and observance of, human rights". In May 1968, ECOSOC Resolution 1296 XLIV specified that NGOs "should have a general international concern with this matter, not restricted to the interests of a particular group of persons, a single nationality or the situation in a single State". While this provision was dropped from the revised text in July 1996, it is still applied in practice. On this basis, the Indian government can block the World Sikh Organization from gaining UN recognition.
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p. 50 67. 1996. Disponvel em: . Acesso em 05 de outubro de 2013. DEEGAN, C. ; BLOMQUIST, C. Stakeholder influence on corporate reporting: An exploration of the interaction between WWF Australia and the Australian minerals industry. Accounting, Organizations and Society, v. 31, p. 343 372.
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